| 1 | Palomino/Cosentino/Wade/Panek-Kravitz | 3:24.48 | 2019 | |
| 2 | Toyne/Garcia/Johnson/Zuluaga(State) | 3:25.02 | 2015 | |
| 3 | McNally/Catro/Miranda/Morris | 3:27.43 | 2022 | |
| 4 | Toyne/Meyers/Palomino/Panek-Kravitz | 3:28.02 | 2018 | |
| 5 | Rodriguez/Johnson/ Garcia/DelRio | 3:29.45 | 2014 | |
| 6 | Guzman, Park, Koesner, Simmons | 3:29.67 | 2007 | |
| 7 | Seton | 3:30.22e | 2000 | |
| 8 | Toyne/Meyers/Knecht/Panek-Kravitz | 3:30.30 | 2017 | |
| 9 | Paloomino/ Wade /Snedeker/Cosentino | 3:30.82 | 2019 | |
| 9 | Garcia/Williams/Llanas/Stoft | 3:30.82 | 2024 | |
| 10 | Palomino/Lind/Toyne/Panek-Kravitz | 3:30.83 | 2018 | |
| 11 | Paloomino/ Wade /Snedeker/Panek-Kravitz | 3:31.10 | 2019 | |
| 12 | Audi/Richard/Tassoti/Scott/Krick/Melcher | 3:31.45e | 1998 | |
| 13 | Creech/Llanas/Welp Garcia | 3:32.00 | 2023 | |
| 14 | Sandell/?/?/? | 3:32.07 | 2004 | |
| 15 | Guzman/Fernandez/Abernethy/Sandell | 3:32.84 | 2006 | |
| 16 | Johnson/Rodriguez/D.Lopez/DelRio | 3:33.00 | 2014 | |
| 17 | Wade/Toyne/DeCaro/Panek-Kravitz | 3:33.62 | 2017 | |
| 18 | Seton | 3:33.74e | 2001 | |
| 19 | Seton | 3:33.79 | 1997 | |
| 20 | Rapier/Toyne/Holton/Garcia | 3:34.02 | 2015 | |
| 21 | Cosentino/Shewbridge/Snedeker/Palomino | 3:34.31 | 2020 | |
| 22 | Stoft/Llanas/Dalacas/Garcia | 3:34.54 | 2024 | |
| 23 | Johnson/Rodriguez/Garcia/Eze | 3:35.06 | 2014 | |
| 24 | Seton | 3:35.30 | 1998 | |
| 25 | Connelly/Levin/Hurtado/Steele | 3:35.41 | 2025 | |
| 26 | Korte/Sandell/Swan/Gorski | 3:36.00 | 2004 | |
| 27 | VanBruwaene/Palomino/Knecht/Panek-Kravitz | 3:36.02 | 2017 | |
| 28 | Fernandez, DeLaTorre, Guzman, Koestner | 3:36.25 | 2006 | |
| 29 | Seton | 3:36.64 | 1998 | |
| 30 | Toyne/Garcia/Holton/Zuluaga | 3:36.77 | 2016 | |
| 31 | Seton | 3:36.85 | 1999 | |
| 32 | Seton | 3:36.91 | 2025 | |
| 33 | Seton | 3:37.17 | 2006 | |
| 34 | Toyne/Wade/Wallace/Pakek-Kravitz | 3:37.80 | 2018 | |
| 35 | Hurtado/Steele/Williams/Levin | 3:37.90 | 2025 | |
| 36 | Park/Davis/Guzman/Koestner | 3:38.08 | 2007 | |
| 37 | Weldon/Bayda/Vance/Nowak | 3:38.18 | 2008 | |
| 38 | Bayda/Vance/Prinz/Polowski | 3:38.18 | 2010 | |
| 39 | Creech/Garcia/Hurtado/Welp | 3:38.35 | 2023 | |
| 40 | Z.Albanese/Williams/Llanas/Stoft | 3:38.37 | 2024 | |
| 41 | Seton | 3:38.4 | 2006 | |
| 42 | J.Koestner/Gorski?/? | 3:38.5 | 2004 | |
| 43 | Toyne/Garcia/Haden/Zuluaga | 3:38.7 | 2016 | |
| 44 | Wade/DeCaro/Panek-Kravitz/Knecht | 3:39.22 | 2017 | |
| 45 | Paterick/Romero/Garcia//Zuluaga | 3:39.30 | 2016 | |
| 46 | Palomino/Cosentino/Monks/Lind | 3:39.33 | 2018 | |
| 47 | Seton | 3:39.62 | 2008 | |
| 48 | Anthony/Llamas/Hermes/Garcia | 3:40.39 | 2024 | |
| 49 | Seton (SEV) | 3:40.50 | 2012 | |
| 50 | Koestner/Sandell/Polowski/Magnus | 3:40.5 | 2005 | |
| 51 | Johnson/Johnson/Agnes/Russell | 3:41.37 | 2013 | |
| 52 | Estes/DeCaro/Eviston/Kulak | 3:41.81 | 2018 | |
| 53 | Seton(St.Meet) | 3:41.48 | 1996 | |
| 54 | Davis/Nowak/Kirkman/Gleisner | 3:41.53 | 2008 | |
| 55 | Seton | 3:41.96 | 2012 | |
| 56 | Seton | 3:42.13 | 2007 | |
| 57 | Seton | 3:42.22 | 2006 | |
| 58 | Palomino/Knecht/Cosentino/Lind (frosh-soph) | 3:42.52 | 2018 | |
| 59 | Johnson/Holten/Garcia/Zulaga | 3:42.5 | 2015 | |
| 60 | Johnson/Johnson/Agnes/s.Lopez | 3:43.07 | 2013 | |
| 61 | Korte, Carter, Swan, Sande | 3:43.50 | 2004 | |
| 62 | Estes/Kulak/Shipley/Meyers | 3:43.57 | 2017 | |
| 63 | Morris/McNally/Miranda/Carrasco | 3:43.59 | 2022 | |
| 63 | Deno Dalacas/Llanas/Williams/Garcia | 3:43.59 | 2024 | |
| 64 | Gorski/Swan/Sandell/Kuner | 3:43.82 | 2004 | |
